This schedule indicates
the recommended ages for routine administration of currently licensed childhood
vaccines, as of December 1, 2007, for children aged 0 through 6 years.
Additional information is
available at www.cdc.gov/vaccines/recs/schedules. Any dose not
administered at the recommended age should be administered at any subsequent
visit, when indicated and feasible. Additional vaccines may be licensed and
recommended during the year. Licensed combination vaccines may be used whenever
any components of the combination are indicated and other components of the
vaccine are not contraindicated and if approved by the U.S. Food and Drug
Administration for that dose of the series. Providers should consult the
respective Advisory Committee on Immunization Practices statement for detailed
recommendations, including for high-risk conditions: www.cdc.gov/vaccines/pubs/ACIP-list.htm.
adverse events that follow immunization should be reported to the Vaccine
Adverse Event Reporting System (VAERS). Guidance about how to obtain and
complete VAERS form is available at www.vaers.hhs.gov or by telephone at 1-800-822-7967.
Click Here to download/view the schedule
1. Hepatitis B
vaccine (HepB). (Minimum age: birth)
- Administer monovalent HepB to all newborns prior to hospital discharge.
- If mother is hepatitis surface antigen (HBsAg)-positive, administer HepB
and 0.5 mL of hepatitis B immune globulin (HBIG)
within 12 hours of birth.
- If mother’s HBsAg
status is unknown, administer HepB within 12
hours of birth. Determine the HBsAg status as
soon as possible and if HBsAg-positive,
administer HBIG (no later than age 1 week).
- If mother is HBsAg-negative,
the birth dose can be delayed,
in rare cases, with a provider’s order and a copy of the mother’s
negative HBsAg laboratory report in the infant’s
After the birth
- The HepB series should be
completed with either monovalent HepB or a combination vaccine containing HepB. The second dose should be administered at age
1–2 months. The final dose should be administered no earlier than
age 24 weeks. Infants born to HBsAg-positive
mothers should be tested for HBsAg and antibody
to HBsAg after completion of at least 3 doses of
a licensed HepB series, at age 9–18 months
(generally at the next well-child visit).
- It is permissible to administer 4 doses of HepB when combination vaccines are administered after
the birth dose. If monovalent HepB is used for doses after the birth dose, a dose at
age 4 months is not needed.
vaccine (Rota). (Minimum age: 6 weeks)
- Administer the first dose at age 6 to12 weeks.
- Do not start the series later than age 12 weeks.
- Administer the final dose in the series by age 32
weeks. Do not administer any dose later than age 32 weeks.
- Data on safety and efficacy outside of these age
ranges are insufficient.
3. Diphtheria and
tetanus toxoids and acellular
pertussis vaccine (DTaP).
(Minimum age: 6 weeks)
- The fourth dose of DTaP may
be administered as early as age 12 months, provided 6 months have elapsed
since the third dose.
- Administer the final dose in the series at age 4 to 6
4. Haemophilus influenzae type b conjugate vaccine (Hib).
(Minimum age: 6 weeks)
- If PRP-OMP (PedvaxHIB®
or ComVax® [Merck]) is
administered at ages 2 and 4 months, a dose at age 6 months is not required.
- TriHIBit® (DTaP/Hib)
combination products should not be used for primary immunization but can
be used as boosters following any Hib vaccine in
children age 12 months or older.
vaccine. (Minimum age: 6 weeks for pneumococcal conjugate
vaccine [PCV]; 2 years for pneumococcal polysaccharide vaccine [PPV])
- Administer one dose of PCV to all healthy children
aged 24 to 59 months having any incomplete schedule.
- Administer PPV to children aged 2 years and older
with underlying medical conditions.
vaccine. (Minimum age: 6 months for trivalent inactivated
influenza vaccine [TIV]; 2 years for live, attenuated influenza vaccine [LAIV])
- Administer annually to children aged 6 to 59 months
and to all close contacts of children aged 0 to 59 months.
- Administer annually to children 5 years of age and
older with certain risk factors, to other persons (including household
members) in close contact with persons in groups at higher risk, and to
any child whose parents request vaccination.
- For healthy nonpregnant
persons (those who do not have underlying medical conditions that
predispose them to influenza complications) ages 2 to 49 years, either
LAIV or TIV may be used.
- Children receiving TIV should receive 0.25 mL if age 6-35 mos or 0.5 mL if age 3 years or older.
- Administer 2 doses (separated by 4 weeks or longer)
to children younger than 9 years who are receiving influenza vaccine for
the first time or who were vaccinated for the first time last season, but
only received one dose.
Measles, mumps, and rubella vaccine (MMR). (Minimum age: 12 months)
- Administer the second dose of MMR at age 4 to 6
years. MMR may be administered before age 4 to 6 years, provided more than
4 weeks have elapsed since the first dose and both doses are administered
at age 12 months or older.
8. Varicella vaccine. (Minimum
age: 12 months)
- Administer second dose at age 4 to 6 years; may be
administered 3 months or more after first dose.
- Don’t repeat second dose if administered 28
days or more after first dose.
9. Hepatitis A
vaccine (HepA). (Minimum age: 12 months)
- HepA is recommended for all
children aged 1 yr (i.e., aged 12 to 23 months). The 2 doses in the series
should be administered at least 6 months apart.
- Children not fully vaccinated by age 2 years can be
vaccinated at subsequent visits.
- HepA is recommended for certain
other groups of children, including in areas where vaccination programs
target older children.
vaccine. (Minimum age: 2 years for meningococcal conjugate
vaccine [MCV4] and for meningococcal polysaccharide vaccine [MPSV4])
- MCV4 is recommended for children aged 2 to 10 years
with terminal complement deficiencies or anatomic or functional asplenia and certain other high-risk groups. Use of
MPSV4 is also acceptable.
- Persons who received MPSV4 3 or more years prior and
remain at increased risk for meningococcal disease should be vaccinated
The Childhood and
Adolescent Immunization Schedule is approved by: Advisory Committee on
Immunization Practices, American Academy of Pediatrics, American Academy of
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